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Showing 1 to 12 of 15195 entries
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The Critical Impact of HIF-1a on Gastric Cancer Biology.

Cancers

Kitajima Y, Miyazaki K.
PMID: 24216696
Cancers (Basel). 2013 Jan 10;5(1):15-26. doi: 10.3390/cancers5010015.

Hypoxia inducible factor-1 (HIF-1) monitors the cellular response to the oxygen levels in solid tumors. Under hypoxia conditions, HIF-1a protein is stabilized and forms a heterodimer with the HIF-1β subunit. The HIF-1 complex activates the transcription of numerous target...

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Kitajima Y, Miyazaki K. The Critical Impact of HIF-1a on Gastric Cancer Biology. Cancers (Basel). 2013;5(1):15-26doi: 10.3390/cancers5010015.
Kitajima, Y., & Miyazaki, K. (2013). The Critical Impact of HIF-1a on Gastric Cancer Biology. Cancers, 5(1), 15-26. https://doi.org/10.3390/cancers5010015
Kitajima, Yoshihiko, and Miyazaki, Kohji. "The Critical Impact of HIF-1a on Gastric Cancer Biology." Cancers vol. 5,1 (2013): 15-26. doi: https://doi.org/10.3390/cancers5010015
Kitajima Y, Miyazaki K. The Critical Impact of HIF-1a on Gastric Cancer Biology. Cancers (Basel). 2013 Jan 10;5(1):15-26. doi: 10.3390/cancers5010015. PMID: 24216696; PMCID: PMC3730315.
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Hepatocyte Growth Factor/c-Met Signaling in Head and Neck Cancer and Implications for Treatment.

Cancers

Rothenberger NJ, Stabile LP.
PMID: 28441771
Cancers (Basel). 2017 Apr 24;9(4). doi: 10.3390/cancers9040039.

Aberrant signaling of the hepatocyte growth factor (HGF)/c-Met pathway has been identified as a promoter of tumorigenesis in several tumor types including head and neck squamous cell carcinoma (HNSCC). Despite a relatively low c-Met mutation frequency, overexpression of HGF...

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Rothenberger NJ, Stabile LP. Hepatocyte Growth Factor/c-Met Signaling in Head and Neck Cancer and Implications for Treatment. Cancers (Basel). 2017;9(4)doi: 10.3390/cancers9040039.
Rothenberger, N. J., & Stabile, L. P. (2017). Hepatocyte Growth Factor/c-Met Signaling in Head and Neck Cancer and Implications for Treatment. Cancers, 9(4), . https://doi.org/10.3390/cancers9040039
Rothenberger, Natalie J, and Stabile, Laura P. "Hepatocyte Growth Factor/c-Met Signaling in Head and Neck Cancer and Implications for Treatment." Cancers vol. 9,4 (2017). doi: https://doi.org/10.3390/cancers9040039
Rothenberger NJ, Stabile LP. Hepatocyte Growth Factor/c-Met Signaling in Head and Neck Cancer and Implications for Treatment. Cancers (Basel). 2017 Apr 24;9(4). doi: 10.3390/cancers9040039. PMID: 28441771; PMCID: PMC5406714.
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Non-Canonical Hh Signaling in Cancer-Current Understanding and Future Directions.

Cancers

Gu D, Xie J.
PMID: 26343727
Cancers (Basel). 2015 Aug 27;7(3):1684-98. doi: 10.3390/cancers7030857.

As a major regulatory pathway for embryonic development and tissue patterning, hedgehog signaling is not active in most adult tissues, but is reactivated in a number of human cancer types. A major milestone in hedgehog signaling in cancer is...

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Gu D, Xie J. Non-Canonical Hh Signaling in Cancer-Current Understanding and Future Directions. Cancers (Basel). 2015;7(3):1684-98doi: 10.3390/cancers7030857.
Gu, D., & Xie, J. (2015). Non-Canonical Hh Signaling in Cancer-Current Understanding and Future Directions. Cancers, 7(3), 1684-98. https://doi.org/10.3390/cancers7030857
Gu, Dongsheng, and Xie, Jingwu. "Non-Canonical Hh Signaling in Cancer-Current Understanding and Future Directions." Cancers vol. 7,3 (2015): 1684-98. doi: https://doi.org/10.3390/cancers7030857
Gu D, Xie J. Non-Canonical Hh Signaling in Cancer-Current Understanding and Future Directions. Cancers (Basel). 2015 Aug 27;7(3):1684-98. doi: 10.3390/cancers7030857. PMID: 26343727; PMCID: PMC4586790.
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The Impact of DNA Repair Pathways in Cancer Biology and Therapy.

Cancers

Nikolaev A, Yang ES.
PMID: 28925933
Cancers (Basel). 2017 Sep 19;9(9). doi: 10.3390/cancers9090126.

Genomic instability is one of the key hallmarks of cancer progression [1].[...].

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Nikolaev A, Yang ES. The Impact of DNA Repair Pathways in Cancer Biology and Therapy. Cancers (Basel). 2017;9(9)doi: 10.3390/cancers9090126.
Nikolaev, A., & Yang, E. S. (2017). The Impact of DNA Repair Pathways in Cancer Biology and Therapy. Cancers, 9(9), . https://doi.org/10.3390/cancers9090126
Nikolaev, Anatoly, and Yang, Eddy S. "The Impact of DNA Repair Pathways in Cancer Biology and Therapy." Cancers vol. 9,9 (2017). doi: https://doi.org/10.3390/cancers9090126
Nikolaev A, Yang ES. The Impact of DNA Repair Pathways in Cancer Biology and Therapy. Cancers (Basel). 2017 Sep 19;9(9). doi: 10.3390/cancers9090126. PMID: 28925933; PMCID: PMC5615341.
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Novel Immunotherapeutic Approaches for Head and Neck Squamous Cell Carcinoma.

Cancers

Bann DV, Deschler DG, Goyal N.
PMID: 27669306
Cancers (Basel). 2016 Sep 22;8(10). doi: 10.3390/cancers8100087.

The immune system plays a key role in preventing tumor formation by recognizing and destroying malignant cells. For over a century, researchers have attempted to harness the immune response as a cancer treatment, although this approach has only recently...

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Bann DV, Deschler DG, Goyal N. Novel Immunotherapeutic Approaches for Head and Neck Squamous Cell Carcinoma. Cancers (Basel). 2016;8(10)doi: 10.3390/cancers8100087.
Bann, D. V., Deschler, D. G., & Goyal, N. (2016). Novel Immunotherapeutic Approaches for Head and Neck Squamous Cell Carcinoma. Cancers, 8(10), . https://doi.org/10.3390/cancers8100087
Bann, Darrin V, et al. "Novel Immunotherapeutic Approaches for Head and Neck Squamous Cell Carcinoma." Cancers vol. 8,10 (2016). doi: https://doi.org/10.3390/cancers8100087
Bann DV, Deschler DG, Goyal N. Novel Immunotherapeutic Approaches for Head and Neck Squamous Cell Carcinoma. Cancers (Basel). 2016 Sep 22;8(10). doi: 10.3390/cancers8100087. PMID: 27669306; PMCID: PMC5082377.
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Histone Modifications, Modifiers and Readers in Melanoma Resistance to Targeted and Immune Therapy.

Cancers

Gallagher SJ, Tiffen JC, Hersey P.
PMID: 26426052
Cancers (Basel). 2015 Sep 25;7(4):1959-82. doi: 10.3390/cancers7040870.

The treatment of melanoma has been revolutionized by new therapies targeting MAPK signaling or the immune system. Unfortunately these therapies are hindered by either primary resistance or the development of acquired resistance. Resistance mechanisms involving somatic mutations in genes...

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Gallagher SJ, Tiffen JC, Hersey P. Histone Modifications, Modifiers and Readers in Melanoma Resistance to Targeted and Immune Therapy. Cancers (Basel). 2015;7(4):1959-82doi: 10.3390/cancers7040870.
Gallagher, S. J., Tiffen, J. C., & Hersey, P. (2015). Histone Modifications, Modifiers and Readers in Melanoma Resistance to Targeted and Immune Therapy. Cancers, 7(4), 1959-82. https://doi.org/10.3390/cancers7040870
Gallagher, Stuart J, et al. "Histone Modifications, Modifiers and Readers in Melanoma Resistance to Targeted and Immune Therapy." Cancers vol. 7,4 (2015): 1959-82. doi: https://doi.org/10.3390/cancers7040870
Gallagher SJ, Tiffen JC, Hersey P. Histone Modifications, Modifiers and Readers in Melanoma Resistance to Targeted and Immune Therapy. Cancers (Basel). 2015 Sep 25;7(4):1959-82. doi: 10.3390/cancers7040870. PMID: 26426052; PMCID: PMC4695870.
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MicroRNAs and Chinese Medicinal Herbs: New Possibilities in Cancer Therapy.

Cancers

Hong M, Wang N, Tan HY, Tsao SW, Feng Y.
PMID: 26305257
Cancers (Basel). 2015 Aug 24;7(3):1643-57. doi: 10.3390/cancers7030855.

In recent decades Chinese medicine has been used worldwide as a complementary and alternative medicine to treat cancer. Plenty of studies have shown that microRNAs (miRNAs) play fundamental roles in many pathological processes, including cancer, while the anti-cancer mechanisms...

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Hong M, Wang N, Tan HY, et al. MicroRNAs and Chinese Medicinal Herbs: New Possibilities in Cancer Therapy. Cancers (Basel). 2015;7(3):1643-57doi: 10.3390/cancers7030855.
Hong, M., Wang, N., Tan, H. Y., Tsao, S. W., & Feng, Y. (2015). MicroRNAs and Chinese Medicinal Herbs: New Possibilities in Cancer Therapy. Cancers, 7(3), 1643-57. https://doi.org/10.3390/cancers7030855
Hong, Ming, et al. "MicroRNAs and Chinese Medicinal Herbs: New Possibilities in Cancer Therapy." Cancers vol. 7,3 (2015): 1643-57. doi: https://doi.org/10.3390/cancers7030855
Hong M, Wang N, Tan HY, Tsao SW, Feng Y. MicroRNAs and Chinese Medicinal Herbs: New Possibilities in Cancer Therapy. Cancers (Basel). 2015 Aug 24;7(3):1643-57. doi: 10.3390/cancers7030855. PMID: 26305257; PMCID: PMC4586788.
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The Androgen Receptor and VEGF: Mechanisms of Androgen-Regulated Angiogenesis in Prostate Cancer.

Cancers

Eisermann K, Fraizer G.
PMID: 28394264
Cancers (Basel). 2017 Apr 10;9(4). doi: 10.3390/cancers9040032.

Prostate cancer progression is controlled by the androgen receptor and new blood vessel formation, or angiogenesis, which promotes metastatic prostate cancer growth. Angiogenesis is induced by elevated expression of vascular endothelial growth factor (VEGF). VEGF is regulated by many...

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Eisermann K, Fraizer G. The Androgen Receptor and VEGF: Mechanisms of Androgen-Regulated Angiogenesis in Prostate Cancer. Cancers (Basel). 2017;9(4)doi: 10.3390/cancers9040032.
Eisermann, K., & Fraizer, G. (2017). The Androgen Receptor and VEGF: Mechanisms of Androgen-Regulated Angiogenesis in Prostate Cancer. Cancers, 9(4), . https://doi.org/10.3390/cancers9040032
Eisermann, Kurtis, and Fraizer, Gail. "The Androgen Receptor and VEGF: Mechanisms of Androgen-Regulated Angiogenesis in Prostate Cancer." Cancers vol. 9,4 (2017). doi: https://doi.org/10.3390/cancers9040032
Eisermann K, Fraizer G. The Androgen Receptor and VEGF: Mechanisms of Androgen-Regulated Angiogenesis in Prostate Cancer. Cancers (Basel). 2017 Apr 10;9(4). doi: 10.3390/cancers9040032. PMID: 28394264; PMCID: PMC5406707.
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Analysis of Pre-Analytic Factors Affecting the Success of Clinical Next-Generation Sequencing of Solid Organ Malignancies.

Cancers

Chen H, Luthra R, Goswami RS, Singh RR, Roy-Chowdhuri S.
PMID: 26343728
Cancers (Basel). 2015 Aug 28;7(3):1699-715. doi: 10.3390/cancers7030859.

Application of next-generation sequencing (NGS) technology to routine clinical practice has enabled characterization of personalized cancer genomes to identify patients likely to have a response to targeted therapy. The proper selection of tumor sample for downstream NGS based mutational...

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Chen H, Luthra R, Goswami RS, et al. Analysis of Pre-Analytic Factors Affecting the Success of Clinical Next-Generation Sequencing of Solid Organ Malignancies. Cancers (Basel). 2015;7(3):1699-715doi: 10.3390/cancers7030859.
Chen, H., Luthra, R., Goswami, R. S., Singh, R. R., & Roy-Chowdhuri, S. (2015). Analysis of Pre-Analytic Factors Affecting the Success of Clinical Next-Generation Sequencing of Solid Organ Malignancies. Cancers, 7(3), 1699-715. https://doi.org/10.3390/cancers7030859
Chen, Hui, et al. "Analysis of Pre-Analytic Factors Affecting the Success of Clinical Next-Generation Sequencing of Solid Organ Malignancies." Cancers vol. 7,3 (2015): 1699-715. doi: https://doi.org/10.3390/cancers7030859
Chen H, Luthra R, Goswami RS, Singh RR, Roy-Chowdhuri S. Analysis of Pre-Analytic Factors Affecting the Success of Clinical Next-Generation Sequencing of Solid Organ Malignancies. Cancers (Basel). 2015 Aug 28;7(3):1699-715. doi: 10.3390/cancers7030859. PMID: 26343728; PMCID: PMC4586792.
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Feasibility of Primary Tumor Culture Models and Preclinical Prediction Assays for Head and Neck Cancer: A Narrative Review.

Cancers

Dohmen AJ, Swartz JE, Van Den Brekel MW, Willems SM, Spijker R, Neefjes J, Zuur CL.
PMID: 26343729
Cancers (Basel). 2015 Aug 28;7(3):1716-42. doi: 10.3390/cancers7030858.

Primary human tumor culture models allow for individualized drug sensitivity testing and are therefore a promising technique to achieve personalized treatment for cancer patients. This would especially be of interest for patients with advanced stage head and neck cancer....

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Dohmen AJ, Swartz JE, Van Den Brekel MW, et al. Feasibility of Primary Tumor Culture Models and Preclinical Prediction Assays for Head and Neck Cancer: A Narrative Review. Cancers (Basel). 2015;7(3):1716-42doi: 10.3390/cancers7030858.
Dohmen, A. J., Swartz, J. E., Van Den Brekel, M. W., Willems, S. M., Spijker, R., Neefjes, J., & Zuur, C. L. (2015). Feasibility of Primary Tumor Culture Models and Preclinical Prediction Assays for Head and Neck Cancer: A Narrative Review. Cancers, 7(3), 1716-42. https://doi.org/10.3390/cancers7030858
Dohmen, Amy J C, et al. "Feasibility of Primary Tumor Culture Models and Preclinical Prediction Assays for Head and Neck Cancer: A Narrative Review." Cancers vol. 7,3 (2015): 1716-42. doi: https://doi.org/10.3390/cancers7030858
Dohmen AJ, Swartz JE, Van Den Brekel MW, Willems SM, Spijker R, Neefjes J, Zuur CL. Feasibility of Primary Tumor Culture Models and Preclinical Prediction Assays for Head and Neck Cancer: A Narrative Review. Cancers (Basel). 2015 Aug 28;7(3):1716-42. doi: 10.3390/cancers7030858. PMID: 26343729; PMCID: PMC4586791.
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KRAS, TP53, CDKN2A, SMAD4, BRCA1, and BRCA2 Mutations in Pancreatic Cancer.

Cancers

Cicenas J, Kvederaviciute K, Meskinyte I, Meskinyte-Kausiliene E, Skeberdyte A, Cicenas J.
PMID: 28452926
Cancers (Basel). 2017 Apr 28;9(5). doi: 10.3390/cancers9050042.

Pancreatic cancer is a disease that has a very high fatality rate and one of the highest mortality ratios among all major cancers, remaining the fourth leading cause of cancer-related deaths in developed countries. The major treatment of pancreatic...

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Cicenas J, Kvederaviciute K, Meskinyte I, et al. KRAS, TP53, CDKN2A, SMAD4, BRCA1, and BRCA2 Mutations in Pancreatic Cancer. Cancers (Basel). 2017;9(5)doi: 10.3390/cancers9050042.
Cicenas, J., Kvederaviciute, K., Meskinyte, I., Meskinyte-Kausiliene, E., Skeberdyte, A., & Cicenas, J. (2017). KRAS, TP53, CDKN2A, SMAD4, BRCA1, and BRCA2 Mutations in Pancreatic Cancer. Cancers, 9(5), . https://doi.org/10.3390/cancers9050042
Cicenas, Jonas, et al. "KRAS, TP53, CDKN2A, SMAD4, BRCA1, and BRCA2 Mutations in Pancreatic Cancer." Cancers vol. 9,5 (2017). doi: https://doi.org/10.3390/cancers9050042
Cicenas J, Kvederaviciute K, Meskinyte I, Meskinyte-Kausiliene E, Skeberdyte A, Cicenas J. KRAS, TP53, CDKN2A, SMAD4, BRCA1, and BRCA2 Mutations in Pancreatic Cancer. Cancers (Basel). 2017 Apr 28;9(5). doi: 10.3390/cancers9050042. PMID: 28452926; PMCID: PMC5447952.
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The Mesothelial Origin of Carcinoma Associated-Fibroblasts in Peritoneal Metastasis.

Cancers

Rynne-Vidal A, Jiménez-Heffernan JA, Fernández-Chacón C, López-Cabrera M, Sandoval P.
PMID: 26426054
Cancers (Basel). 2015 Sep 29;7(4):1994-2011. doi: 10.3390/cancers7040872.

Solid tumors are complex and unstructured organs that, in addition to cancer cells, also contain other cell types. Carcinoma-associated fibroblasts (CAFs) represent an important population in the tumor microenviroment and participate in several stages of tumor progression, including cancer...

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Rynne-Vidal A, Jiménez-Heffernan JA, Fernández-Chacón C, et al. The Mesothelial Origin of Carcinoma Associated-Fibroblasts in Peritoneal Metastasis. Cancers (Basel). 2015;7(4):1994-2011doi: 10.3390/cancers7040872.
Rynne-Vidal, A., Jiménez-Heffernan, J. A., Fernández-Chacón, C., López-Cabrera, M., & Sandoval, P. (2015). The Mesothelial Origin of Carcinoma Associated-Fibroblasts in Peritoneal Metastasis. Cancers, 7(4), 1994-2011. https://doi.org/10.3390/cancers7040872
Rynne-Vidal, Angela, et al. "The Mesothelial Origin of Carcinoma Associated-Fibroblasts in Peritoneal Metastasis." Cancers vol. 7,4 (2015): 1994-2011. doi: https://doi.org/10.3390/cancers7040872
Rynne-Vidal A, Jiménez-Heffernan JA, Fernández-Chacón C, López-Cabrera M, Sandoval P. The Mesothelial Origin of Carcinoma Associated-Fibroblasts in Peritoneal Metastasis. Cancers (Basel). 2015 Sep 29;7(4):1994-2011. doi: 10.3390/cancers7040872. PMID: 26426054; PMCID: PMC4695872.
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Showing 1 to 12 of 15195 entries